Thursday, October 6, 2016

How Does Spiriva Work? Is it for me?

Spiriva is a brand of anticholinergic medication that dilates airwaysand facilitates breathing in patients with Chronic Obstructive Pulmonary Disease (COPD). It contains the “active” drug molecule Tiotropium. It should be used only to prevent the common symptoms of COPD which include wheezing, shortness of breath (SOB), coughing, and chest tightness.

This medication is available in the form of a capsule, the contents of which are to be inhaled using a specialized device that comes with it. The device is called HandiHaler.

Continue reading to discover more on how Spiriva works and to learn more about its Uses, Side effects, and Dosage.

How does Spiriva help you breathe?

When Spiriva is inhaled, the powder inside the capsule reaches inner walls of the bronchi (singular: bronchus). Bronchi are two tube-like structures that branch from the base of the wind-pipe and connect to each lung. It works on specific target sites (receptors) in the bronchi and inhibits receptor-mediated bronchoconstriction. Then,the muscles of the bronchi are relaxed,providing more space for better air flow.

Studies also suggest that Spiriva may reduce production of mucus, which provides better air flow.

When can you use Spiriva?

You can use Spiriva only after your doctor recommends it for you. You have to keep in mind that Spiriva is meant for maintenance therapy of COPD, meaning that it can be used for a long period of time to control the symptoms of COPD, helping you breathe more easily. However, it should not be used when you have attacks of COPD that occur suddenly. For serious attacks of COPD symptoms, your doctor will prescribe some other medications. Talk to your doctor to learn if you are eligible to use Spiriva.

Uses of Spiriva

The capsules of Spiriva are inhaled using the HandiHaler to prevent wheezing, breathing difficulties, chest discomfort, and coughing in patients with COPD. Ask your doctor to learn how to use the HandiHaler properly.

Dosage of Spiriva

The way Spiriva works is slightly different from other similar drugs like Ipratropium. The bronchodilating effects of Spiriva last for 24 hours or even more after a single dose. A single daily dose is recommended. For more information on doses, read the medication guide carefully and follow accordingly.

Side Effects of Spiriva

Spiriva is associated with various side effects, some of which are non-serious, while some can be life-threatening. So, it’s wise to take note of any side effect that persists or causes you trouble. For convenience, the side effects of Spiriva may be categorized as:

Common and non-serious side effects

All anticholinergic agents including Spiriva cause dryness of mouth.
You may also have digestive problems including Constipation, abdominal pain, Dyspepsia (indigestion), and painful patches in mouth.
Side effects involving the respiratory system are nosebleeds, runny nose, and sneezing.
Remember that the majority of these side effects improve as your body becomes accustomed to Spiriva.




Uncommon and serious side effects

The following side effects of Spiriva are not so common but can be serious. These include sore throat, fever, and other signs of infection.

You may experience headaches due to inflammation of Sinuses.


Problems related to vision are also considered serious. These include blurred vision or painful and reddened eyes.

Abnormally fast heart rhythm is another cardiac sign that indicates something serious.

Remember not to take any of these side effects lightly. If you notice any of these side effects, consult your doctor right away. Also keep in mind that these side effects could indicate overdose.

Symptoms of Allergy to Spiriva

If you have a known allergy to Tiotropium, other anticholinergic agents, or any ingredient used in the drug preparation, you should not take Spiriva.

If you experience signs of allergy such as hives, rashes, swelling of the lips, tongue, or throat, and breathing difficulties, discontinue treatment right away and ask for emergency medical attention.


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