Tuesday, September 6, 2016

The Truth about Antidepressants and Autism

Antidepressants and Autism


Could your child develop autism because you took antidepressants while pregnant?

There has been an ongoing controversy over the use of antidepressants during pregnancy. Various studies have linked their use to an increased risk of autism developing in their children. However, the dilemma still persists and often creates a confusing environment not only among patients, but also doctors. 

Autism is a group of severe neurological disorders in which a child has difficulties with communication (both verbal and nonverbal), interacting with individuals or responding to certain situations (social aspect), and exhibits repetitive pattern behaviors.

(Further Reading: Symptoms of Autism)

Symptoms start appearing during early childhood and usually continue for life. Today, there is currently no cure for autism. However, there are some treatments that may improve symptoms and help the affected child live a more normal life.

What are SSRI antidepressants? Do they really cause Autism?

SSRI’s (Selective Serotonin Reuptake Inhibitors) are a class of depression-treating medications that work by altering levels of certain chemicals (especially serotonin) in the brain. These medications are more useful in severe cases of depression when other non-drug treatments cannot provide desired results.

Some SSRI examples include Prozac, Zoloft and others. Your doctor can also prescribe SSRI’s to treat anxiety disorders such as social anxiety disorder (SAD or social phobia) and post-traumatic stress disorder (PTSD).


Key Points about antidepressant (SSRI) that should not be missed
     SSRI’s are not contraindicated in pregnancy
     SSRI’s are the drug of choice to treat depression that occurs during pregnancy

Some clues regarding the link between antidepressant and autism are observed in the studies, but there is no causal relationship between the two.

The BIG Question: Should You use Antidepressant during Pregnancy?


The big question is not just about the numbers and stats, it’s about how we can help pregnant women overcome depression, leaving little or no effect on the fetus. Here are some facts to consider before taking antidepressants during pregnancy:

     Untreated depression and its effects on both the pregnant mother and developing child warrant the use of antidepressant during pregnancy. Severe depression remains one of the leading causes of suicide. In addition, anxiety problems during pregnancy can result in low birth weight.
     Studies conducted today are not conclusive, and do not establish antidepressant use during pregnancy as the sole cause of autism in the child.
     Some studies have missed the unhealthy lifestyle of the mother during pregnancy.
     Studies show increased risk is just 0.5%, which is arguably less significant.
     Data shows depression symptoms observed in approximately 10-20% of the future moms. Looking at the prevalence of depression during pregnancy, one cannot simply rule out the use of an antidepressant.
     The perceived risk of autism in children is relatively small, and should not stop the mother from taking measures (both drug and non-drug) to combat symptoms of depression.




Owed to limitations of the studies and lack of direct cause and effect, further large-scale studies are needed to quantify this problem.

Until conclusive results come to fruition, you can use antidepressants during pregnancy, after consulting your doctor. It is important that you continue scheduled visits to the doctor during pregnancy. For mild to moderate depression, you may stop the medication during pregnancy and continue after delivery, if your doctor permits.

Pregnancy is one of the most cherished moments for a family, and such moments should not be marred by depression, or the undesirable effects of antidepressants. A balanced approach in treating depression, while causing no long term harm to the unborn child is what every doctor should make their priority.

For future mothers, stay happy, learn more about risk through reliable sources and keep your doctor informed.

If you are pregnant and taking antidepressants, considering these potential complications, and visit your doctor to discuss the likelihood of antidepressant complications during pregnancy.