Friday, September 30, 2016

Data Raises Concerns About Zetia and Vytorin Side Effects



What is Zetia? 

Zetia is an effective cholesterol-reducing medicine that prevents cholesterol absorption in the intestines. Moreover, it lowers the quantity of cholesterol stored in the liver and helps the body process cholesterol.

What is Vytorin? Vytorin is a well-known combination and cholesterol-reducing medicine. The simvastatin protects your body from producing bad cholesterol, (LDL) while increasing the good cholesterol (HDL). Ezetimibe helps in preventing cholesterol absorption in the intestines while reducing other risk problems.

Data Suggests the drugs have limited benefits
According to some studies, both Zetia and Vytorin have limited benefits. Information from a clinical trial demonstrates that the cholesterol drugs don't produce any health advantages to users when contrasted with high doses of bland Zocor, and they be made susceptible to risk of heart attack and liver problems. 

An article in the New York Times raised concern that Zetia and Vytorin reactions may increase the risk of liver damage when used in combination with statin cholesterol drugs. Concerns about liver damage from Zetia were raised after a spokesman for the medication producers recognized that a few patients were expelled from the Enhance study in the wake of test results showing that they had elevated liver proteins.

Zetia and Vytorin are prevalent medications prescribed for treatment of high cholesterol. Around one million individuals receive one of the medications every week. Zetia, which is produced by Merck and Co. also, Schering-Plow Corp., works by obstructing the ingestion of cholesterol in the digestive tract. Vytorin is a combination drug made by the same organizations, which contains both Zetia and Zocor. 

The study, known as Enhance, found that Zetia and Vytorin symptoms brought on fatty plaques about twice as quick when contrasted to those prescribed Zocor alone. The clinical trial took around 720 people with elevated cholesterol for prolonged periods. Clients of Vytorin and Zetia were observed to pass on or endure heart entanglements as indicated by the information, however given the nature of the trail, outcomes did not achieve the level of measurable effectiveness. This implies the distinctions could have been brought on by chance. Other studies are expected to better assess the risk.  

Statins, which consist of Lipitor, Crestor and Zocor, are regularly recommended with Zetia or as a component of the Vytorin pill, which consolidates Zetia and Zocor. As indicated by the New York Times, there have been a few reports of serious liver damage connected with the use of Zetia and statins, and the combination has appeared to bring about liver damage as well.

The outcomes of the Enhance study were portrayed as "shocking" by Dr. Steven Nissen, the director of cardiology at the Cleveland Clinic, who wrote about the dangers of Avandia heart attack symptoms. Dr. Nissen was one ofthe primary specialists to bring up issues with Vioxx, which was reviewed in 2004. 

Dr. Nisson recommended that Zetia and Vytorin should not be prescribed unless all other cholesterol drugs have failed to work, as the medication has no advantages and may open people to an expanded danger of heart attacks. The FDA has not commented on the information yet.  Speak with your doctor before changing any medications.  The legal advisors at Saiontz & Kirk, P.A. are looking into data about the Zetia, and whether sufficient information has been gathered about the risks and advantages of the medications. To learn more about Zetia and Vytorin, please visit www.FindaTopDoc.com today.